FASCINATION ABOUT KETAMINE AND SEIZURES

Metabolism Ketamine is metabolized via N-dealkylation into the Energetic metabolite norketamine primarily by CYP2B6 and CYP3A4 and also to a lesser extent by other CYP enzymes. Norketamine undergoes hydroxylation of the cyclohexone ring to sort hydroxynorketamine compounds by means of CYP-dependent pathways, which are conjugated with glucuronic aci